- Did cosmic inflation happen or was there another process?
- Is earth the only place in the cosmos with life?
- How [can we] merge general relativity and quantum mechanics?
- What is dark energy and dark matter?
- How did life begin on Earth?
The first question I'd like to read a convincing answer to is how did brute matter - atoms and sub-atomic particles - ever give rise in evolutionary history to human consciousness? Indeed, what exactly is consciousness? It would seem that the explanatory gap between material stuff and conscious experience is enormous so how was it bridged in human development and, for that matter, how is it bridged in each human brain?
The second question I'd like to see answered is what is matter in the first place? What is the fundamental constituent of matter? Is it something solid or is it a force of some kind? If it's the latter then how does solidity arise? Is solidity just an illusion? Is the material world objectively real and to what extent is it so?
Someone might dismiss such questions with the remark that the answers make no difference to how we live our everyday lives, and at one level they'd surely be correct. But, if, as a lot of very smart people think, the answers to these questions would point to an ontic reality beyond the universe itself, an intelligent mind, then the implications for everyday life could be considerable.
If, for example, it should turn out that consciousness cannot arise from matter but must itself be the product of yet another consciousness then it would appear that conscious mind underlies the cosmos, and if it should turn out that matter (or mass/energy) reduces to information then, since information is the product of minds, it would appear, again, that a mind must underlie the cosmos.
Those are conclusions of immense significance for every thinking person.
Perhaps we'll never know the answers. Perhaps we cannot know them. Perhaps solving these puzzles is as far beyond our intellectual capacities as solving quadratic equations is beyond the intellectual capacities of a rabbit. All the same, it'd be a stupendous achievement were the answers ever found.