Bering writes:
Drawing largely from work by psychiatrists, Fisher surmises that there are two main stages associated with a dead and dying romantic relationship, which is of course often preceded by a partner’s infidelities. During the “protest” stage that occurs in the immediate aftermath of rejection:
"Abandoned lovers are generally dedicated to winning their sweetheart back. They obsessively dissect the relationship, trying to establish what went wrong; and they doggedly strategize about how to rekindle the romance. Disappointed lovers often make dramatic, humiliating, or even dangerous entrances into a beloved’s home or place of work, then storm out, only to return and plead anew. They visit mutual haunts and shared friends. And they phone, e-mail and write letters, pleading, accusing and/or trying to seduce their abandoner.
"At the neurobiological level, the protest stage is characterized by unusually heightened, even frantic activity of dopamine and norepinephrine receptors in the brain, which has the effect of pronounced alertness similar to what is found in young animals abandoned by their mothers. This impassioned protest stage—if it proves unsuccessful in re-establishing the romantic relationship—slowly disintegrates into the second stage of heartbreak, what Fisher refers to as “resignation/despair”:
"With time the spurned individual gives up pursuit of the abandoning partner. Then he or she must deal with intensified feelings of helplessness, resignation and despair. Drugged by sorrow, most cry, lie in bed, stare into space, drink too much, or hole up and watch TV. Feelings of protest and anger resurface intermittently, but rejected lovers mostly just feel profound melancholy … Some people in the despair phase of rejection kill themselves. Some die of a broken heart. Broken-hearted lovers expire from heart attacks or strokes caused by their depression … As the abandoned partner realizes that [reunion] will never come, dopamine-making cells in the midbrain decrease their activity [causing] lethargy, despondency and depression."Eventually, most people get over their heartbreak, the dopamine cells regain their vigor, and the person gets on with his or her life. In the meantime, however, some people experiencing this rejection act as if they've gone insane, which, in a way, I suppose they have. It's very sad.